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Selected research from leading health care experts whose findings have a direct bearing on public policies effecting medical progress. Research is chosen based on its quality and relevance by the Medical Progress Today editorial staff.

Selected Research

BNP Better Than C-Reactive Protein at Predicting Cardiovascular Events
Medscape, 4-5-05

Physicians have many options—from statins to diet and exercise—to help treat patients at high risk of coronary artery disease. The trick is finding those patients reliably and easily using tools called biomarkers. Current biomarkers include LDL cholesterol and C-reactive protein—and now “the N-terminal fragment of the prohormone brain natriuretic peptide (NT-proBNP).”

[BNP] is a stronger predictor of cardiovascular disease and death than is C-reactive protein (CRP) in older adults, according to a report in the Journal of the American Medical Association for April 6th…Using the 80th percentile as a cutoff...NT-proBNP levels above this threshold were linked to a 3.24-fold increased risk of a first major cardiovascular event. By contrast, the hazard ratios seen with CRP and the urinary albumin/creatinine ratio were lower-1.02 and 2.32, respectively.


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