Selected research from leading health care experts whose findings have a direct bearing on public policies effecting medical progress. Research is chosen based on its quality and relevance by the Medical Progress Today editorial staff.

Selected Research

Pharmacogenomics: an Assessment of Market Conditions and Competition
Academy Health, 3-1-07

Academy Health finds that the nascent science of pharmacogenomics (PGx), i.e. how drugs interact with genetics, faces several formidable challenges before it can become widespread in the marketplace—particularly because our reimbursement system is badly aligned with the concept of personalized medicine.

Not only do PGx products and services stand to reduce adverse drug reactions, they have the potential to: 1) speed the approval process for drugs, reducing the cost of clinical trials (by using genetic tests to target a defined patient population); 2) reduce the length of time patients are on medication; 3) reduce the number of medications patients must take in order to find an effective therapy; and 4) reduce of the effects of disease in the body through early detection...

This study finds that the existing U.S. payment system is not designed for, and is therefore inadequate for, PGx products and services to reach their maximum treatment potential. The researchers encourage policymakers to discuss and consider reforms to the current financing and payment systems in light of the potential for positive health outcomes. "With the widespread adoption of PGx, a simple genetic test may prevent countless adverse drug events, hospitalizations, disability, and death," says Rossiter. The results of this study indicate that more funding should be directed toward PGx cost–effectiveness research. Only with additional funding directed toward health services research, can society truly experience the greatest value offered by PGx.

Project FDA.
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